Biological monitoring is a complex and sometimes daunting area of occupational and environmental medicine. Clinical Practice of Biological Monitoring, Second Edition provides a clear path for the intricate task of selecting the appropriate laboratory test, the most relevant matrix for testing, or the most informative analyte so as to best interpret a chemical test result for clinical relevance.
Highlights of the second edition:
- Devoted to a single chemical, each chapter contains a quick-guide table indicating the best analyte, the best matrix, and a level-of-concern value for the substance.
- Further, the book identifies chemicals that cannot be measured directly, thereby allowing for time savings and avoidance of unnecessary testing.
- Ten new chapters and updated First Edition chapters, elucidate exposure to chemicals now contemporaneous with commerce or public health.
- Small enough to carry in your pocket!
Determining what test to do for an individual chemical exposure need not be a challenge. Refer to your pocket consultant, Clinical Practice of Biological Monitoring, Second Edition,
for concise guidance on monitoring exposure to chemicals.
NOTE: The eBook version is online access only and NOT downloadable
From the Preface...
Frequently, it is challenging to choose the proper laboratory test,
the most relevant biological matrix for testing, or the most informative
analyte to provide the best interpretation and clinical
relevance to the chemical test result. Our aim was to compose
a practical and clinically relevant guide to biological monitoring.
After years of intensive research, discussion, and writing, we present
Clinical Practice of Biological Monitoring, Second Edition. In addition
to refining previous chapters, this edition contains additional
chapters regarding chemicals that now are contemporaneous
with commerce or public health. However, limited commercially-
available assays constrain the selection of chemicals to include
in this edition.
The subject matter of this text is human exposure to inorganic,
organic, and organometallic substances from industrial and
environmental sources. For the reader, we elucidate occupational,
environmental, and toxicology basics as they pertain to biological
monitoring methods and objectives. We also discuss the interface
of biomonitoring in causal methodology. Moreover, we detail
both advantages and limitations of biological monitoring, as well
as practical pre-analytical and post-analytical considerations.
At the end of each chapter and augmented with figures and
tables, are methods for assessing exposure. Most chapters include
a quick-guide table succinctly indicating the best analyte,
the best matrix, and a level-of-concern value for each substance.
While not a health benchmark, the level-of-concern value is a potential
indicator of a breach in industrial controls or elevated ambient
concentrations requiring further investigation.
Table of Contents
Contributing Authors xi
Section I: Foundations of Biological Monitoring
Introduction to Biological Monitoring
Kelvin Wooller, MB BS (Syd)
Biological Monitoring and Causation
Section II: Individual Chemicals
Ethyl Tertiary Butyl Ether (ETBE) and Methyl Tertiary Butyl Ether
Phenoxyacetic Acid Herbicides